For roads, the M5 motorway between the West Midlands and the West Country and its junction with the M6 motorway passes through the town, making West Bromwich at the hub of Britain's motorway network. Improvements were made at the A41 junction by West Bromwich town centre after a £25 million project grant was awarded to the area to cut congestion for commuters. The junction, which is where The Expressway meets All Saints Way (A4031), currently carries over 60,000 vehicles a day, and is close to Junction 1 of the M5 The project involved the creation of a dual carriageway underpass, beneath an improved roundabout. This work began in June 2010 and was completed in Autumn 2012. West Bromwich has its own bus station in the town centre, with connections to Birmingham, Wolverhampton and other major towns in the West Midlands region.

West Bromwich railway station was opened by the Great Western Railway on its route between Birmingham Snow Hill and Wolverhampton Low Level on 14 November 1854. The track-bed of that line is now served by the West Midlands Metro light rail (tram) system with West Bromwich having seven tram stops: The Hawthorns, Kenrick Park, Trinity Way, West Bromwich Central, Lodge Road West Bromwich Town Hall, Dartmouth Street and Dudley Street Guns Village. The nearest main-line railway station is now Sandwell & Dudley railway station, approximately 1 mile (2 km) away in Oldbury town centre. Though services to Stourbridge Junction, Worcester Shrub Hill, Worcester Foregate Street, and Birmingham Snow Hill, Birmingham Moor Street call at The Hawthorns railway station. There was previously a railway station on Newton Road which was located a mile away from the town centre. It was on the Grand Junction Railway that ran from Birmingham New Street to Stafford via Wolverhampton High Level and Walsall. This station closed in 1945 although it moved two times between 1863 and 1902, only the line remains in use for the services from Walsall to Birmingham, Wolverhampton and Liverpool Lime Street.

The nearest airport which is approximately 16 miles (26 km) away, is Birmingham Airport, which can be reached by tram to Birmingham New Street and train to Birmingham International.

Carters Green, High Street and the beginning of Birmingham Road formed the original main route through West Bromwich as part of Thomas Telford's London to Holyhead route in the early 19th century. This later formed part of the A41 road which links London with Merseyside, taking in the midlands, Shropshire, Warwickshire, Oxfordshire, Buckinghamshire and Hertfordshire on the way. However, the route through central West Bromwich was by-passed in 1973 on the completion of the Expressway, a two-mile (3 km) dual carriageway beginning at Carters Green and finishing at Junction 1 of the recently completed M5 motorway on Birmingham Road. The original A41 road through the centre of West Bromwich was downgraded to an unclassified route.

Around this time, West Bromwich Ringway was opened, circulating the main shopping areas. The section of the Ringway near the new Tesco has since had traffic restrictions placed on it prohibiting use by private cars.

Further revolution came to the local road network in 1995 with the completion of the Black Country Spine Road which stretches from Carters Green to Bilston via Wednesbury, forming another new section of the A41.

West Bromwich has a large bus station managed by Transport for West Midlands and served by a large number of routes, both locally to places such as Oldbury, Smethwick and Stone Cross as well as regional bus routes to places such as Birmingham, Wolverhampton and Walsall. Stands are lettered a through to z. The main bus operators serving the bus station are National Express West Midlands and Diamond West Midlands.